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Gastrointestinal infections

Gastrointestinal infections occurs when bacteria infect the gut and as a result leading to the inflammation of the stomach and the small intestines. Other symptoms of the infections are vomiting, severe abdominal cramps and diarrhea. The infections are as a result of  poor hygiene or after consuming food or water contaminated with bacteria. The symptoms vary according to the bacteria that causes the infection. Treatment is aimed at preventing keeping a patient hydrated to replace the salts and the much water that is also due to diarrhea.

Treatment of the gastrointestinal infections includes taking antibiotics and fluids to keep one hydrated. One of the drugs used in the treatment of gastrointestinal infections is cephalosporin. Cephalosporin disrupts the manufacture of bacterial wall which leads to the collapse of the walls leading to the death of the bacteria (Ferreira et al, 2016). Cephalosporin antibiotics are grouped into generations depending on their spectrum of antimicrobial activity.

The advantage of using the cephalosporin antibiotic is that it has an extensive healing window, it is safe to be used in pregnancy, it has a wide spectrum and finally it is well tolerated. According to Ferreira, cephalosporin have a greater cure rate as compared to other antibiotics like penicillin (Ferreira et al, 2016).

The disadvantages of cephalosporin is that it has varying CSF penetration, the antibiotic cephalosporin is also not efficient for typical respiratory pathogens and finally it has restricted activity against pseudomonas.

Reference

Ferreira, A., Bolland, M. J., & Thomas, M. G. (2016). Meta-analysis of randomized trials comparing a penicillin or cephalosporin with a macrolide or lincosamide in the treatment of cellulitis or erysipelas. Infection, 44(5), 607-615.

 
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